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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC6L All Species: 26.67
Human Site: T229 Identified Species: 41.9
UniProt: Q9Y5N6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y5N6 NP_055136.1 252 28107 T229 P Q K D E D L T Q D Y E E W K
Chimpanzee Pan troglodytes XP_001161833 252 28124 T229 P Q K Y E D L T Q D Y E E W K
Rhesus Macaque Macaca mulatta XP_001113625 252 28130 T229 P Q K D E D L T Q D Y E E W K
Dog Lupus familis XP_539609 252 27646 T229 L Q K D E D L T Q D Y E E W K
Cat Felis silvestris
Mouse Mus musculus Q9WUJ8 262 29170 T239 L P K D E D L T Q D Y E E W K
Rat Rattus norvegicus NP_001028862 262 28796 T239 L P K D A G L T Q D Y E E W K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521050 272 30470 N249 Q Q K S E E L N Q D Y E E W K
Chicken Gallus gallus XP_414114 301 33273 K262 K Q P K T E T K Q D Y E E W K
Frog Xenopus laevis NP_001086912 225 24746 K199 V V N E Q P R K R Q K T L L E
Zebra Danio Brachydanio rerio NP_997836 256 28612 T234 E K T E E E E T H H Y E E W K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y1B2 257 29221 P222 K K A H K P P P E D Y E I W K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793313 204 22972 S182 K S S Q D S N S S K Q D D Y E
Poplar Tree Populus trichocarpa XP_002316713 285 32005 T230 N F S S D D G T E V S S H K K
Maize Zea mays NP_001151122 293 32508 R250 K R R K K M E R E A Y N D W K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVH3 284 31751 K254 S T V V N S I K K N P E K G T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 84.1 N.A. 74.4 70.6 N.A. 66.5 48.5 51.5 51.9 N.A. 26.4 N.A. N.A. 28.5
Protein Similarity: 100 99.2 98.8 90.8 N.A. 85.5 80.1 N.A. 74.6 61.7 65.8 71.4 N.A. 47 N.A. N.A. 45.6
P-Site Identity: 100 93.3 100 93.3 N.A. 86.6 73.3 N.A. 73.3 53.3 0 46.6 N.A. 33.3 N.A. N.A. 0
P-Site Similarity: 100 93.3 100 93.3 N.A. 86.6 73.3 N.A. 80 60 26.6 66.6 N.A. 53.3 N.A. N.A. 40
Percent
Protein Identity: 27.3 26.6 N.A. 25.3 N.A. N.A.
Protein Similarity: 47.3 47.4 N.A. 46.4 N.A. N.A.
P-Site Identity: 20 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: 33.3 53.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 0 0 0 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 34 14 40 0 0 0 60 0 7 14 0 0 % D
% Glu: 7 0 0 14 47 20 14 0 20 0 0 74 60 0 14 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 7 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 7 0 0 0 0 7 7 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % I
% Lys: 27 14 47 14 14 0 0 20 7 7 7 0 7 7 80 % K
% Leu: 20 0 0 0 0 0 47 0 0 0 0 0 7 7 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 7 0 7 0 7 7 0 7 0 7 0 0 0 % N
% Pro: 20 14 7 0 0 14 7 7 0 0 7 0 0 0 0 % P
% Gln: 7 40 0 7 7 0 0 0 54 7 7 0 0 0 0 % Q
% Arg: 0 7 7 0 0 0 7 7 7 0 0 0 0 0 0 % R
% Ser: 7 7 14 14 0 14 0 7 7 0 7 7 0 0 0 % S
% Thr: 0 7 7 0 7 0 7 54 0 0 0 7 0 0 7 % T
% Val: 7 7 7 7 0 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 74 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 74 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _